Alcohol Pharmacotherapy for HIV+ Prisoners
Diseases and Conditions Researched
AIDS; Alcohol Dependence; Hazardous Drinking; Human Immunodeficiency Virus; Problem Drinking
What is the purpose of this trial?
This is a randomized controlled trial of injectable intramuscular naltrexone (XR-NTX) versus intramuscular placebo among HIV-infected prisoners meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for alcohol dependence or problem drinking, who are transitioning to the community and seeking treatment to prevent relapse to alcohol use. We hypothesize that extended release naltrexone (XR-NTX) will result in improved HIV outcomes (lower log10 HIV-1RNA levels and higher CD4 count) as well as improved alcohol treatment outcomes, and reduced drug/sex HIV related risk behaviors and decreased rates of reincarceration.
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|Sponsors:||National Institute on Alcohol Abuse and Alcoholism (NIAAA); Yale University|
|Dates:||February 19, 2010|
|Last Updated:||August 4, 2011|
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