PET Imaging in Cocaine Self Administration

Diseases and Conditions Researched

Cocaine Dependence

What is the purpose of this trial?

There has been recent interest in the role of the 5-HT1B receptor as a possible modulating factor in cocaine dependence, certainly in preclinical models. The Yale Positron Emission Tomography (PET) Center has developed a novel 5-HT1B receptor antagonist radioligand, [11C]-P943, which has been validated in human studies. We hypothesize that the 5-HT1B receptor plays a key role in cocaine dependence. The long term goal of this project would be to study pharmacological manipulation of the 5-HT1B receptor as a potential molecular target for cocaine dependence.

Participation Guidelines

Age: 18 Years - 50 Years
Gender: Both

This trial accepts healthy volunteers.

Click here for detailed participation information for this trial.

Sponsor: National Institute on Drug Abuse
Last Updated:
Study HIC#: 0811004457