The genetic effect on omega 3 fatty acid diet for the treatment of non alcoholic fatty liver disease in obese children and adolescents

Diseases and Conditions Researched

Alanine Aminotransferase, Plasma Level of, Quantitative Trait Locus 1; Hypertriglyceridemia; Non Alcoholic Fatty Liver Disease; Steatohepatitis

What is the purpose of this trial?

To explore whether there is a different response to the omega-3 fatty acid supplementation vs omega-3 fatty acid rich diet with respect to the hepatic fat fraction % (HFF), triglyceride, and ALT levels between the rs738409 minor allele (GG) and the common allele homozygous (CC) of PNPLA3.

Participation Guidelines

Age: 10 Years - 19 Years
Gender: Both

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Sponsor: Yale University School of Medicine
Last Updated:
Study HIC#: 1112009408