A Phase II Trial of Response-Based Radiation Therapy for Pediatric Patients with Localized Central Nervous System Germ Cell Tumors (CNS GCT)

Diseases and Conditions Researched

Brain and Nervous System

What is the purpose of this trial?

Drugs used as chemotherapy, such as carboplatin, etoposide, and ifosfamide work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x rays to kill tumor cells. Giving chemotherapy with radiation therapy may kill more tumor cells. This phase II trial studies how well chemotherapy and radiation therapy work in treating younger patients with newly diagnosed central nervous system germ cell tumors.

Participation Guidelines

Age: 3 Years - 21 Years
Gender: Both

Click here for detailed participation information for this trial.

Sponsor: Children's Oncology Group (The)
Last Updated:
Study HIC#: 1305011967