A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction (PIONEER-HCM)

What is the purpose of this trial?

The purpose of this phase 2 open-label pilot study is to evaluate the efficacy, pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of MYK-461 in subjects with symptomatic HCM and LVOT obstruction aged 18-70 years.

Participation Guidelines

Ages: 18 - 70 years

Gender: Both

MyoKardia, Inc.

Dates: 10/07/2016 - 05/31/2017

Last Updated: 10/08/2016

Study HIC#: 2000020006

Get Involved

For more information about this study, contact:
Christina L Williams

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

Trial Image


Daniel Louis Jacoby

Principal Investigator