The PhenoGenetic Project

What is the purpose of this trial?

The aim of this project is to determine the role of genetic variation in the diversity of human immune response by testing DNA polymorphisms for association with immunological phenotypes in individuals with no clinical evidence of inflammatory or infectious diseases. In the subject population of this study, immunophenotypes will be characterized from serum and from peripheral blood mononuclear cells (PBMCs). Cytometric, RNA profiling and proteomic platforms will be used in these serological and cellular analyses. This study will genetically dissect human immune gene expression in a cohort of individuals with no clinical evidence of disease, yielding a wealth of data with which to guide the investigation of inflammatory and infectious diseases.


Participation Guidelines

Ages: 18 - 54 years

Gender: Both


Life Science Research Foundation

Dates: 10/12/2010 - 12/31/2025

Last Updated: 02/26/2017

Study HIC#: 1008007275REG

Get Involved

For more information about this study, contact:
Stephanie C Eisenbarth
stephanie.eisenbarth@yale.edu

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 1-877-978-8348.

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Investigators

Stephanie C Eisenbarth

Principal Investigator

Sub-Investigators